乙肝病毒核心抗原,Hepatitis B virus core antigen
1)Hepatitis B virus core antigen乙肝病毒核心抗原
1.Methods:By using gene engineering techniques,we constructed a fusion protein containing the-COOH end of human hepatitis B virus core antigen(HBcAg),small home-to-cancer peptide ligand RGD and Glutathione S-transferase(GST),which was expressed in E.方法:利用基因工程技术,将人乙肝病毒核心抗原(HBcAg)的-COOH端和靶向肿瘤的整和素配体RGD肽与谷胱甘肽还原酶(GST)在大肠埃希菌中融合表达,经分子筛和GST亲和纯化后,获得DNA包装蛋白GST-RGD-ΔHBcAg。
英文短句/例句
1.Studies on Expression of Fusion Gene HAV Epitopes Antigen with HBV Core Antigen;甲肝病毒表位抗原与乙肝病毒核心抗原融合基因表达的研究
2.Studies on Cloning and Expression of Fusion Gene Combining HCV Epitopes Antigen with HBV Core Antigen;丙肝病毒复合多表位抗原与乙肝病毒核心抗原融合基因的克隆及表达
3.The Capacity of Antigen Presentation of BMDCs Enhanced by HBc-VLPs;乙肝病毒核心抗原病毒样颗粒负载的树突状细胞抗原提呈能力的研究
4.The Effects of HBV Core Antigen and Truncated Middle Hepatitis B Surface Protein on Trail-Induced Apoptosis and Its Molecular Mechanisms;乙肝病毒核心抗原和截短型中蛋白对TRAIL诱导肝细胞凋亡的影响及分子机制研究
5.Study on the Transactivating Function of HBcAg Antigen;乙型肝炎病毒核心抗原反式激活作用的研究
6.Clinical Significance of Dynamic Evaluation of Combined Detection of Hepatitis B Virus Pre S1 Antigen and Core Antigen动态评价联合检测乙肝病毒前S1抗原与核心抗原的临床意义
7.Experimental Study on Membrane Expression of Hepatitis B Core Antigen in HepG2 Cells;乙型肝炎病毒核心抗原在HepG2细胞膜表达的实验研究
8.SYNTHESIS OF GENE ENCODING HEPATITIS B CORE BY OVERLAPPING PCR AND ITS EXPRESSION IN ESCHERICHIA COLI重叠PCR合成乙型肝炎病毒核心抗原基因及其在大肠杆菌中表达
9.Construction of duck hepatitis B virus core antigen DNA vaccine and induced humoral immune response鸭乙型肝炎病毒核心抗原DNA疫苗的构建及其诱导的体液免疫应答
10.HEPATITIS B VIRUS (HBV) DNA DETECTION ANALYSIS OF HEPATITIS B SURFACE ANTIGEN (HBSAG) POSITIVE SERUM乙肝表面抗原阳性反应血清的乙肝病毒核酸检测分析
11.Detection of hepatitis B virus DNA in blood donors with anti-HBc positive and analysis of S gene variation乙型肝炎核心抗体阳性献血者乙肝病毒DNA检测及基因变异分析
12.Evaluation of 5 Kinds of China-made Enzyme Immuoassay Kits for Antibody to Hepatitis B Virus Core Antigen Detection五种国产酶免疫测定法抗乙型肝炎病毒核心抗原抗体检测试剂的评价
13.The effect of codon optimization on the immunogenicity of middle hepatitis B surface antigen DNA vaccine密码子优化对乙肝病毒表面抗原中蛋白核酸疫苗免疫原性的影响
14.Construction of DNA Vaccine Against Herpes simplex virus by Using the Fusion Gene of Herpes simplex virus Type Ⅱ(HSV-2) Dominant Epitope and Hepatitis B Core Protein单纯疱疹病毒Ⅱ型抗原优势表位与乙肝核心蛋白融合DNA疫苗的构建
15.The Study on the Initial Virological Response of Nucleoside Analogs in Chronic Hepatitis B核苷类药物抗乙肝病毒的早期病毒学应答研究
16.Cloning and Prokaryotic Expression X Protein of Hepatitis B Virus (HBx) and Preparation and Identification of Monoclonal Antibody Against It;乙型肝炎病毒X蛋白的原核表达及单克隆抗体的制备和鉴定
17.The influence of anti-HBc antibody on patients after renal transplantation乙型病毒性肝炎核心抗体阳性对肾移植患者影响的临床研究
18.Development of time-resolved fluoroimmunoassay kit for detection of IgM antibodies against hepatitis B core antigen乙型肝炎病毒核心抗体IgM时间分辨荧光免疫分析试剂盒的研制
相关短句/例句
HBcAg乙肝病毒核心抗原
3)HBV Core Antigen乙肝病毒核心抗原
1.Studies on Cloning and Expression of Fusion Gene Combining HCV Epitopes Antigen withHBV Core Antigen;丙肝病毒复合多表位抗原与乙肝病毒核心抗原融合基因的克隆及表达
2.Studies on Expression of Fusion Gene HAV Epitopes Antigen withHBV Core Antigen;甲肝病毒表位抗原与乙肝病毒核心抗原融合基因表达的研究
4)hepatitis B virus C antigen乙肝病毒核心抗原
1.Construction of eukaryotic expression vector containinghepatitis B virus C antigen gene and CpG motifand identification of expressed protein in dendritic cells;插入CpG序列的乙肝病毒核心抗原基因真核表达质粒的构建及在树突状细胞中的表达
2.Construction and identification of eukaryotic expression vector containinghepatitis B virus C antigen gene and CpG motif;插入CpG序列的乙肝病毒核心抗原基因真核表达质粒的构建及鉴定
5)Hepatitis B virus core antigen乙型肝炎病毒核心抗原
1.Construction and in vitro expression of bicistronic DNA vaccines containing hepatitis B virus core antigen and Flt3 ligand genes;乙型肝炎病毒核心抗原及Flt3配体双表达核酸疫苗的构建与体外表达
6)HbcAg乙型肝炎病毒核心抗原
1.Objective To activate peripheral blood B lymphocytes by CpG-oligodeoxynucleotides(CpG-ODN) and load HBcAg 18-27 peptide to make them as antigen presenting cells(APC),then induce hepatitis B virus(HBV)-specific cytolytic T lymphocytes(CTL) from peripheral blood monocular cells(PBMC) of healthy human.目的探讨负载乙型肝炎病毒核心抗原18-27(HBcAg 18-27)序列肽的活化B淋巴细胞诱导自体外周血单个核细胞(PBMC)产生HBcAg 18-27特异性细胞毒性T淋巴细胞(CTL)的能力。
延伸阅读
乙肝病毒核心抗原分子式:CAS号:性质:由病毒基因组上C基因编码区的第二个ATG起始的,为一部分磷酸化的21 000道尔顿的蛋白质。180个HBcAg分子装配成直径27nm的核心颗粒。大肠杆菌表达的HBcAg也能形成颗粒。HBcAg有很好的免疫原性,比HBsAg(子核表面抗原)大80倍。它诱导产生的抗体有依赖T细胞和不依赖T细胞两种,而且还有很强的细胞免疫应答。因此有人认为理想的乙肝疫苗应该同时具有HBsAg及HBcAg的免疫决定簇。
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